Hannibal Regional Healthcare System

America’s Heartland

Nestled along the Mississippi River, Hannibal is best known as the boyhood home of Mark Twain and the inspiration for The Adventures of Tom Sawyer and Adventures of Huckleberry Finn.

  • Population just under 20,000, with a strong sense of community
  • More parks per capita than most Midwest towns
  • Expanding trail systems for hiking and biking
  • Easy access to boating on the Mississippi River and nearby lakes
  • A thriving arts scene, part of the renowned “50 Miles of Art”
  • Diverse local economy with stable, affordable housing
  • Convenient location 1.5 hours north of St. Louis, MO

Hannibal’s historic downtown, walking tours, artisan studios, and locally owned shops create a unique and vibrant place to live and work.

Our Location

Title / Specialty Facility Location Posted
Neurologist | Competitive Base + More!Neurology Apply Hannibal Regional Healthcare System Hannibal, Missouri 2026-04-14
Radiologist | $550K Base + 13 Weeks PTO | No NightsRadiology Apply Hannibal Regional Healthcare System Hannibal, Missouri 2026-04-14
Hematology / Oncology Physician | $650K Base + WRVU UpsideHematology/Oncology Apply Hannibal Regional Healthcare System Hannibal, Missouri 2026-04-14
Family Medicine Physician | Above MGMA Median + 31 Days PTOFamily Medicine Apply Hannibal Regional Healthcare System Hannibal, Missouri 2026-04-14
Cardiology Opportunity | $610K Salary + $100K Loan RepaymentCardiology Apply Hannibal Regional Healthcare System Hannibal, Missouri 2026-04-14
Child & Adolescent Psychiatrist – Outpatient Only | $50K Sign-On + $100K Loan RepaymentPsychiatry - Child & Adolescent Apply Hannibal Regional Healthcare System Hannibal, Missouri 2026-04-14
Geriatric / Palliative Care Physician | Above MGMA + $50K Sign-OnGeriatric Medicine Apply Hannibal Regional Healthcare System Hannibal, Missouri 2026-04-14
Primary Care in Mark Twain Country | Loan Repayment IncludedFamily Medicine Apply Hannibal Regional Healthcare System Hannibal, Missouri 2026-04-14
General Orthopedic SurgeonOrthopedic Surgery Apply Hannibal Regional Healthcare System Hannibal, Missouri 2026-04-14
Gastroenterologist | $100K+ Sign-On + Guaranteed BaseGastroenterology Apply Hannibal Regional Healthcare System Hannibal, Missouri 2026-04-14
Internal Medicine Physician | $360K Salary + $50K Sign-OnInternal Medicine Apply Hannibal Regional Healthcare System Hannibal, Missouri 2026-04-14
Program Director - Internal Medicine (New Program North of STL)Internal Medicine Apply Hannibal Regional Healthcare System Hannibal, Missouri 2026-04-14
General Anesthesiologist - Hannibal, MOAnesthesiology Apply Hannibal Regional Healthcare System Hannibal, Missouri 2026-04-14